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Open Access Genome database

The updated RGD Pathway Portal utilizes increased curation efficiency and provides expanded pathway information

G Thomas Hayman*, Pushkala Jayaraman, Victoria Petri, Marek Tutaj, Weisong Liu, Jeff De Pons, Melinda R Dwinell and Mary Shimoyama

Author Affiliations

Rat Genome Database, Human and Molecular Genetics Center, Medical College of Wisconsin, Milwaukee, WI 53226, USA

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Human Genomics 2013, 7:4  doi:10.1186/1479-7364-7-4

Published: 5 February 2013

Abstract

The RGD Pathway Portal provides pathway annotations for rat, human and mouse genes and pathway diagrams and suites, all interconnected via the pathway ontology. Diagram pages present the diagram and description, with diagram objects linked to additional resources. A newly-developed dual-functionality web application composes the diagram page. Curators input the description, diagram, references and additional pathway objects. The application combines these with tables of rat, human and mouse pathway genes, including genetic information, analysis tool and reference links, and disease, phenotype and other pathway annotations to pathway genes. The application increases the information content of diagram pages while expediting publication.

Keywords:
Curation; Databases; Ontologies; Pathways; Tools